1
From: "Human Potential & Development."
Split Justification: Development fundamentally involves both our inner landscape (**Internal World**) and our interaction with everything outside us (**External World**). (Ref: Subject-Object Distinction)..
2
From: "Internal World (The Self)"
Split Justification: The Internal World involves both mental processes (**Cognitive Sphere**) and physical experiences (**Somatic Sphere**). (Ref: Mind-Body Distinction)
3
From: "Somatic Sphere"
Split Justification: The Somatic Sphere encompasses all physical aspects of the self. These can be fundamentally divided based on whether they are directly accessible to conscious awareness and subjective experience (e.g., pain, touch, proprioception) or whether they operate autonomously and beneath the threshold of conscious perception (e.g., heart rate, digestion, cellular metabolism). Every bodily sensation, state, or process falls into one of these two categories, making them mutually exclusive and comprehensively exhaustive.
4
From: "Conscious Somatic Experience"
Split Justification: Conscious somatic experiences can be fundamentally divided based on whether their primary focus is on the body's internal condition, physiological state, or spatial configuration (e.g., hunger, proprioception, pain from an organ, fatigue) or whether they are primarily concerned with the body's interaction, contact, or perception of stimuli from the external environment (e.g., touch, temperature, pressure, pain from an external source). These two categories are mutually exclusive as an experience's primary referent is either internal or external to the body's boundary, and comprehensively exhaustive as all conscious somatic experiences fall into one of these two fundamental domains.
5
From: "Awareness of Internal Bodily States"
Split Justification: All conscious awareness of internal bodily states can be fundamentally categorized as either perceptions related to the body's internal homeostatic balance, health, and drives (e.g., hunger, thirst, pain from organs, fatigue) or perceptions related to the body's physical configuration, posture, and locomotion in space (e.g., proprioception, kinesthesia, balance). These two categories are distinct in their primary sensory input and functional purpose, making them mutually exclusive and comprehensively exhaustive for internal bodily awareness.
6
From: "Awareness of Physiological Needs and States"
Split Justification: All conscious awareness of physiological needs and states fundamentally relates to either a deviation from homeostasis, indicating a problem, lack, or threat (physiological discomfort or deficiency), or the successful maintenance or restoration of homeostasis, indicating well-being or met needs (physiological comfort or sufficiency). These two categories are mutually exclusive as a sensation cannot simultaneously signal a problem and its resolution, and comprehensively exhaustive as any conscious physiological state will fall into one of these two fundamental domains.
7
From: "Awareness of Physiological Discomfort or Deficiency"
Split Justification: ** All conscious awareness of physiological discomfort or deficiency can be fundamentally categorized based on whether the primary subjective experience is that of pain—a specific, often highly aversive sensation signaling actual or potential tissue damage—or a distinct type of unpleasant physiological state or sensation of lack (e.g., hunger, thirst, fatigue, nausea, itch, dizziness). These two categories are mutually exclusive as a conscious sensation is primarily identified as either pain or not pain, and comprehensively exhaustive as all forms of physiological discomfort or deficiency fall into one of these two fundamental experiential types.
8
From: "Awareness of Physiological Pain"
Split Justification: ** All conscious awareness of physiological pain can be fundamentally categorized by its primary anatomical and physiological origin. It either arises from the detection of actual or threatened damage to non-neural tissues via healthy nociceptors (referred to as nociceptive pain), or it arises from a lesion, disease, or altered processing within the somatosensory nervous system itself (encompassing both neuropathic pain and nociplastic pain). These two categories are mutually exclusive as a pain sensation's primary genesis is either external to or internal to the nervous system's proper functioning, and comprehensively exhaustive as all recognized forms of physiological pain fall into one of these two fundamental domains.
9
From: "Awareness of Pain Originating from Nervous System Dysfunction"
Split Justification: All conscious awareness of pain originating from nervous system dysfunction can be fundamentally categorized based on whether it is directly caused by a demonstrable lesion or disease of the somatosensory nervous system (neuropathic pain), or if it arises from altered nociceptive processing in the absence of such a lesion or disease (nociplastic pain). These two categories are mutually exclusive as the primary etiology involves either a demonstrable structural abnormality or a functional processing alteration without a primary structural lesion, and comprehensively exhaustive as all recognized forms of pain originating from nervous system dysfunction fall into one of these two fundamental mechanisms.
10
From: "Awareness of Nociplastic Pain"
Split Justification: All conscious awareness of nociplastic pain, arising from altered nociceptive processing without clear tissue damage or structural neural lesion, can be fundamentally categorized by the predominant underlying neurophysiological dysregulation. This dysregulation involves either an inappropriate amplification of pain signals due to heightened excitability and synaptic efficacy within the central nervous system (enhanced central sensitization), or a failure of the brain's intrinsic pain-modulating pathways to adequately suppress incoming or ongoing nociceptive signals (impaired descending inhibition). These two mechanisms represent distinct, though often interacting, fundamental alterations in how the nervous system processes pain, making them mutually exclusive as primary functional deficits and comprehensively exhaustive in describing the core mechanisms of nociplastic pain.
11
From: "Awareness of Nociplastic Pain from Impaired Descending Inhibition"
Split Justification: All conscious awareness of nociplastic pain originating from impaired descending inhibition can be fundamentally categorized based on whether the primary dysfunction lies in the higher brain centers and their pathways *generating and transmitting* the inhibitory signals, or in the spinal cord's capacity to *receive, process, and effectively respond* to these inhibitory signals. These two categories represent distinct points of failure within the descending pain modulation system, making them mutually exclusive as the core mechanism of impairment and comprehensively exhaustive for describing all forms of impaired descending inhibition.
12
From: "Awareness of Nociplastic Pain from Impaired Spinal Cord Responsiveness to Descending Inhibition"
Split Justification: All conscious awareness of nociplastic pain originating from impaired spinal cord responsiveness to descending inhibition can be fundamentally categorized based on whether the primary dysfunction lies in the *efficacy of synaptic transmission* where descending inhibitory pathways connect to spinal cord pain-processing neurons (e.g., issues with neurotransmitter release, receptor function, or immediate post-synaptic transduction), or if it lies in the *intrinsic electrophysiological properties or baseline excitability* of the spinal cord pain circuits themselves, rendering them less susceptible to inhibition even if synaptic transmission is intact. These two categories are mutually exclusive as one focuses on the efficiency of the inhibitory signal's transfer to the spinal cord neurons, and the other on the inherent state of those neurons that dictates their response; together, they comprehensively exhaust the fundamental ways the spinal cord's capacity to receive and effectively respond to descending inhibitory signals can be impaired.
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Topic: "Awareness of Nociplastic Pain from Impaired Synaptic Transmission of Descending Inhibition to Spinal Cord" (W6017)